APC - anti Human CD56 - B-A19

Reference Size Price Quantity Add to cart
56A1-100T 100 test
230,00 €

Product Description

  • B-A19
  • IgG1
  • FCM
  • APC
  • Please refer to the Certificate of Analysis for the lot-specific concentration.
  • U937 cell line (Human)
  • Human
  • The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
  • RUO
  • CD56, clone B-A19, is a mAb valid for identification of Natural Killer (NK) Cells and a subpopulation of T lymphocytes. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
  • Link
CD56 View larger
This antibody reacts with the CD56-antigen, which is expressed in lymphocytes mediating non-MHC restricted cytotoxicity and is present on some neural tissues and tumors. It is expressed on natural killer (NK) Cells and a subpopulation of T lymphocytes. NK cells make up approximately 10-25% of peripheral blood lymphocytes. This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Expression of neural cell adhesion molecules (N-CAM) provides neurons with a means of attaching to and interacting with other cells and the extracellular matrix. There are describes 6 isoforms produced by alternative splicing of N-CAM mRNA. The three major isoforms are referred to as 180 kD, 140 kD, and 120 kD. Individual isoforms undergo various post-translational modifications, including the addition of polysialic acid residues to embryonic forms. The highly polysialylated forms of N-CAM present in embryos and neonates are lost during maturation and replaced by less-polysialic acid-laden mature forms of N-CAM. The functional significance of alternative forms of N-CAM remain to be fully elucidated.
  • Leu-19, NKH1, NCAM, CAMPATH-1 antige, CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, Human epididymis-specific protein 5, He9
  • 4684
  • 175-185kDa

Tech Data Sheet


Technical Data Sheet

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Technical Data Sheet