FITC - anti Human CD16 - 3G8

Reference Size Price Quantity Add to cart
16F2-100T 100 test
200,00 €

Product Description

  • 3G8
  • IgG1
  • FCM
  • FITC
  • Please refer to the Certificate of Analysis for the lot-specific concentration.
  • Human polymorphonuclear leukocytes
  • Human
  • The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
  • IVD-CE
  • CD16 clone 3G8, mAb is used for identify/enumerate human antigen (FcRIII). It´s an antipan FcγRIII (CD16) whereas clone GRM1 recognizes NA2-FcRIIIb & FcRIIIa. It´s effective for direct IF staining of human tissue for FCM tests using ≤1 μg/106 cells.
  • Store in the dark at 2-8 ºC
  • Link

This antibody reacts with the CD16-antigen. CD16 exists as two distinct isoforms, FcγRIIIA and FcγRIIIB. In humans, FcγRIIIA is expressed as a polypeptide-anchored form on monocytes, macrophages, and lymphocytes such as NK cells. T and B cells do not express this Fc receptor. FcγRIIIB is also detected on neutrophils as a GPI-anchored form. Expression of CD16 on lymphocytes and monocytes is similar in non-human primates. Binding of IgG leads to activation of signal transduction pathways, resulting in antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, cytokine release, and antigen presentation.

  • FCRIII, Fc-gamma receptor IIIb, CD16, FCG3, FCGR3, IGFR5
  • 2214
  • 50-65 kDa

Tech Data Sheet


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Technical Data Sheet