The minimum purchase order quantity for the product is 1
Armenian Hamster IgG
mouse Fc epsilon receptor I (FceR1) alpha subunit
The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
FcεRIα Antibody, clone MAR-1, is a mAb intended for RUO in the identification of cells that express FcεRIα (Basophils and Mast Cells). This reagent is effective for direct IF staining of mouse sample for FCM analysis using ≤1 µg/106 cells.
The MAR-1 monoclonal antibody reacts with the Fc epsilon Receptor I alpha subunit, an IgE-binding subunit lacking signal-transducing ability. Fc epsilon RI alpha; is expressed on mast and basophil cells and is up-regulated by the presence of IgE. Fc epsilon RI alpha forms a tetrameric complex with one beta and two gamma subunits. The beta and gamma subunits possess immunoreceptor tyrosine-based activation motifs (ITAM). The Fc epsilon RI complex plays an important role in triggering IgE-mediated allergic reactions